Motif ID: FOX{I1,J2}.p2

Z-value: 1.314


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ2chr12_+_8185241-0.629.8e-02Click!
FOXI1chr5_+_1695329000.403.3e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_14992166 1.183 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr11_+_63304272 0.923 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr10_+_111967302 0.904 NM_130439
MXI1
MAX interactor 1
chr13_-_86373328 0.817 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr1_+_84764048 0.807 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr8_+_104383785 0.723 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr3_+_136676706 0.694 NM_144717
IL20RB
interleukin 20 receptor beta
chr6_+_26365397 0.679 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr9_-_95244634 0.667 ASPN
asporin
chr8_-_108510094 0.665 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr8_+_104383701 0.650 CTHRC1
collagen triple helix repeat containing 1
chr3_-_169587598 0.621 NM_024727
LRRC31
leucine rich repeat containing 31
chr12_+_27175482 0.606 NM_004264
MED21
mediator complex subunit 21
chr13_+_97928196 0.580 MBNL2
muscleblind-like 2 (Drosophila)
chr17_-_19290471 0.557 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr1_-_108231122 0.549 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr12_+_27175501 0.548 MED21
mediator complex subunit 21
chr12_-_15038724 0.514 NM_000900
NM_001190839
MGP

matrix Gla protein

chr14_-_81864726 0.508 NM_033104
STON2
stonin 2
chr6_+_5030202 0.504 LOC100129461
uncharacterized LOC100129461
chr1_+_84768333 0.501 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr9_-_95244750 0.496 NM_001193335
NM_017680
ASPN

asporin

chr19_+_36486042 0.486 NM_001042631
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr3_-_121379701 0.484 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr4_-_100242487 0.474 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr3_-_121379757 0.472 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_111415721 0.463 NM_000560
CD53
CD53 molecule
chr1_+_171060017 0.462 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr4_+_89299874 0.460 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr4_-_186578122 0.450 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr3_-_189838673 0.440 LEPREL1
leprecan-like 1
chr7_+_76026819 0.436 NM_007155
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr8_-_93111915 0.429 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_89299980 0.421 HERC6
hect domain and RLD 6
chrX_+_135278912 0.419 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr6_+_69344939 0.408 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr14_+_70918873 0.404 NM_003813
ADAM21
ADAM metallopeptidase domain 21
chr1_+_44064509 0.403 PTPRF
protein tyrosine phosphatase, receptor type, F
chr4_+_86749045 0.398 ARHGAP24
Rho GTPase activating protein 24
chr1_+_74701070 0.395 NM_015978
TNNI3K
TNNI3 interacting kinase
chr12_-_50790391 0.384 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr12_+_10365415 0.382 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr17_+_7942351 0.382 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr9_-_95298251 0.380 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr12_+_20848288 0.376 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr10_-_90712510 0.373 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr8_+_86099909 0.368 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr4_-_138453628 0.365 NM_019035
PCDH18
protocadherin 18
chr9_+_131683173 0.360 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr15_+_25068793 0.356 NM_022806
NM_022807
NM_022808
SNRPN


small nuclear ribonucleoprotein polypeptide N


chr20_+_123230 0.355 NM_030931
DEFB126
defensin, beta 126
chr2_+_166095911 0.350 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr4_-_186577858 0.349 SORBS2
sorbin and SH3 domain containing 2
chr13_+_97794050 0.345 MBNL2
muscleblind-like 2 (Drosophila)
chr9_+_12774988 0.344 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr2_+_233498206 0.343 NM_025202
EFHD1
EF-hand domain family, member D1
chr3_+_158787040 0.342 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr12_-_121735558 0.342 CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr8_-_93107442 0.341 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr19_-_4831711 0.334 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr2_+_207804277 0.333 NM_173077
CPO
carboxypeptidase O
chr21_+_30517897 0.331 C21orf7
chromosome 21 open reading frame 7
chr8_+_120079423 0.328 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr18_-_24220307 0.326 NM_198991
KCTD1
potassium channel tetramerisation domain containing 1
chr10_+_111969988 0.320 NM_001008541
MXI1
MAX interactor 1
chr3_-_189838907 0.318 NM_018192
LEPREL1
leprecan-like 1
chr3_-_111851967 0.311 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr1_+_111415791 0.309 CD53
CD53 molecule
chr1_+_151739130 0.308 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr3_-_114343052 0.307 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr8_-_24772229 0.303 NEFM
neurofilament, medium polypeptide
chr19_-_4338750 0.302 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr7_-_97601564 0.298 MGC72080
MGC72080 pseudogene
chr19_-_39264144 0.297 NM_002307
LGALS7
LGALS7B
lectin, galactoside-binding, soluble, 7
lectin, galactoside-binding, soluble, 7B
chr2_-_216878314 0.296 NM_018000
MREG
melanoregulin
chr7_+_76054251 0.292 NM_001110354
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr18_+_616671 0.285 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr11_-_57335756 0.285 NM_198183
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr7_-_97601637 0.279 MGC72080
MGC72080 pseudogene
chr9_+_127054246 0.278 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr1_+_155100304 0.275 NM_004428
NM_182685
EFNA1

ephrin-A1

chr11_-_13517525 0.272 NM_000315
PTH
parathyroid hormone
chr22_-_46659218 0.271 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr10_-_46619935 0.268 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr20_-_44538654 0.267 PLTP
phospholipid transfer protein
chr12_+_47610051 0.267 NM_138371
FAM113B
family with sequence similarity 113, member B
chr7_+_6617035 0.265 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr19_+_1026271 0.261 NM_004368
NM_201277
CNN2

calponin 2

chr8_-_93107881 0.257 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr1_-_110933683 0.256 NM_001201546
NM_001201547
NM_001201548
NM_001201549
NM_004696
SLC16A4




solute carrier family 16, member 4 (monocarboxylic acid transporter 5)




chr12_-_122107559 0.255 NM_173855
MORN3
MORN repeat containing 3
chr10_+_124145584 0.254 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr8_-_17658385 0.253 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr3_+_189349215 0.252 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr15_+_89182038 0.249 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_58430394 0.248 NM_020980
AQP9
aquaporin 9
chr8_+_144640476 0.247 NM_024736
GSDMD
gasdermin D
chr4_-_100212085 0.247 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr1_-_110933635 0.247 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr7_+_150811719 0.246 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr19_-_54567034 0.244 NM_198481
VSTM1
V-set and transmembrane domain containing 1
chrX_+_80457302 0.243 NM_003022
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr17_-_50236950 0.242 CA10
carbonic anhydrase X
chr19_+_50879681 0.240 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr19_+_36024313 0.240 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr18_-_52626636 0.239 NM_025214
CCDC68
coiled-coil domain containing 68
chr14_+_37126772 0.239 NM_006194
PAX9
paired box 9
chr1_+_82266081 0.238 NM_012302
LPHN2
latrophilin 2
chr10_-_48806862 0.237 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr5_-_36301999 0.236 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr17_-_7531107 0.234 NM_133491
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr7_-_25268057 0.234 NM_022150
NPVF
neuropeptide VF precursor
chr9_-_100935173 0.233 NM_003389
CORO2A
coronin, actin binding protein, 2A
chr1_+_145096391 0.233 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr13_+_23755059 0.231 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr5_+_166711842 0.229 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr15_+_25101697 0.228 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr19_+_17337012 0.228 NM_024578
OCEL1
occludin/ELL domain containing 1
chr8_+_75736771 0.227 NM_015886
PI15
peptidase inhibitor 15
chr8_-_7220489 0.227 NM_001164457
ZNF705G
zinc finger protein 705G
chr17_+_40703983 0.226 NM_000413
HSD17B1
hydroxysteroid (17-beta) dehydrogenase 1
chr3_-_151034514 0.223 NM_023915
GPR87
G protein-coupled receptor 87
chr17_+_57408907 0.222 NM_001005404
YPEL2
yippee-like 2 (Drosophila)
chr6_+_26501448 0.220 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr17_-_56494889 0.217 RNF43
ring finger protein 43
chr12_+_26348488 0.217 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr6_-_144416633 0.217 SF3B5
splicing factor 3b, subunit 5, 10kDa
chr13_+_97928414 0.216 MBNL2
muscleblind-like 2 (Drosophila)
chr10_-_103540125 0.216 NM_001206389
FGF8
fibroblast growth factor 8 (androgen-induced)
chr4_-_70826712 0.213 NM_001891
CSN2
casein beta
chr18_-_56296188 0.213 NM_052947
ALPK2
alpha-kinase 2
chr19_-_18654280 0.212 FKBP8
FK506 binding protein 8, 38kDa
chr1_+_77333158 0.212 NM_030965
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr22_+_45148437 0.212 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr19_+_44080951 0.211 NM_001193621
LOC390940
uncharacterized protein ENSP00000244321
chr1_-_153599523 0.210 NM_001024213
S100A13
S100 calcium binding protein A13
chr11_+_59522801 0.208 STX3
syntaxin 3
chr16_+_31128973 0.207 NM_032188
NM_182958
KAT8

K(lysine) acetyltransferase 8

chr10_+_118187381 0.207 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr13_-_78493902 0.205 NM_001201397
EDNRB
endothelin receptor type B
chr13_+_32420828 0.204 EEF1DP3
eukaryotic translation elongation factor 1 delta pseudogene 3
chr1_-_168698412 0.204 NM_001937
DPT
dermatopontin
chr20_+_58251715 0.202 NM_001199506
PHACTR3
phosphatase and actin regulator 3
chr17_+_67410825 0.201 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr22_+_32753853 0.201 NM_001098535
RFPL3
ret finger protein-like 3
chr1_+_150122415 0.200 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr5_+_55147206 0.200 NM_001242637
NM_001242638
NM_139017
IL31RA


interleukin 31 receptor A


chr3_-_58563070 0.199 FAM107A
family with sequence similarity 107, member A
chr10_-_98031154 0.199 NM_001114094
NM_013314
BLNK

B-cell linker

chr1_+_86889768 0.197 NM_006536
CLCA2
chloride channel accessory 2
chr20_+_48552928 0.197 RNF114
ring finger protein 114
chr2_+_162016926 0.196 NM_001199135
TANK
TRAF family member-associated NFKB activator
chr4_-_138453564 0.195 PCDH18
protocadherin 18
chr6_-_138820580 0.195


chr3_-_15382874 0.194 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr17_-_29624249 0.194 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr11_+_59522905 0.193 STX3
syntaxin 3
chr14_-_45431121 0.193 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr17_-_34195745 0.193 NM_152781
C17orf66
chromosome 17 open reading frame 66
chr4_+_147096834 0.193 NM_007080
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_-_150329285 0.192 GIMAP6
GTPase, IMAP family member 6
chr14_-_94595915 0.191 IFI27L2
interferon, alpha-inducible protein 27-like 2
chr9_+_118916069 0.187 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr7_+_26331611 0.186 SNX10
sorting nexin 10
chr8_+_123794043 0.186 ZHX2
zinc fingers and homeoboxes 2
chr4_+_3315873 0.186 NM_002926
NM_198229
RGS12

regulator of G-protein signaling 12

chr5_+_138677570 0.186 PAIP2
poly(A) binding protein interacting protein 2
chr14_-_94595925 0.185 NM_032036
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr6_-_144416753 0.184 NM_031287
SF3B5
splicing factor 3b, subunit 5, 10kDa
chr2_+_181845803 0.184 UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr8_-_19540093 0.183 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr19_-_36499583 0.183 NM_001039876
C19orf46
chromosome 19 open reading frame 46
chr3_-_165555167 0.182 BCHE
butyrylcholinesterase
chr5_+_138677517 0.182 NM_016480
PAIP2
poly(A) binding protein interacting protein 2
chr16_+_68678150 0.180 NM_001793
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr11_+_64085602 0.180 PRDX5
peroxiredoxin 5
chr6_+_30856462 0.179 NM_001202521
NM_001202522
NM_013994
DDR1


discoidin domain receptor tyrosine kinase 1


chr17_-_42144986 0.179 NM_152344
LSM12
LSM12 homolog (S. cerevisiae)
chr5_+_40841296 0.178 NM_032587
CARD6
caspase recruitment domain family, member 6
chr2_-_144994905 0.177 NM_024659
GTDC1
glycosyltransferase-like domain containing 1
chr5_+_81601165 0.177 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr3_-_187463474 0.177 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr17_+_1665281 0.176 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_+_76320106 0.175 HNF4G
hepatocyte nuclear factor 4, gamma
chr22_-_37098620 0.175 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr11_+_32851469 0.174 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr1_+_155099935 0.174 EFNA1
ephrin-A1
chr3_-_165555252 0.174 NM_000055
BCHE
butyrylcholinesterase
chr11_-_111782447 0.174 NM_001885
CRYAB
crystallin, alpha B
chr14_-_22005035 0.172 NM_005407
SALL2
sal-like 2 (Drosophila)
chr6_+_88032289 0.172 NM_001042493
NM_020425
C6orf162

chromosome 6 open reading frame 162

chr5_+_138677546 0.171 PAIP2
poly(A) binding protein interacting protein 2
chr11_-_104827421 0.171 NM_033306
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr17_+_1665306 0.170 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr18_+_61554938 0.169 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr8_-_110657745 0.169 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr17_+_1665233 0.169 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_+_23845932 0.168 NM_001037288
NM_138460
CMTM5

CKLF-like MARVEL transmembrane domain containing 5

chr5_+_32711437 0.168 NM_000908
NM_001204375
NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

chr1_+_77333121 0.168 ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 9.34e-03 GO:0023052 signaling
1.13 9.40e-03 GO:0065007 biological regulation
1.22 1.07e-02 GO:0032502 developmental process
1.13 2.48e-02 GO:0050789 regulation of biological process
1.22 4.36e-02 GO:0007275 multicellular organismal development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.07 3.26e-02 GO:0005488 binding